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No specific dose adjustment advised when tofacitinib coadministered with powerful CYP2C19 inhibitors; lower tofacitinib dose if coadministered with equally average CYP3A4 and strong CYP2C19 inhibitors .Edgar and Seidel (1997) investigated the consequences of modafinil on snooze-wake EEG and locomotor exercise in Reside rats in comparison with the c